Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 7/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.32 |
| ▸ | TAF1 | P21675 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19663716 | 0.82 | GRM2 (0.32) | — | |
| SCHEMBL17749777 | 0.72 | CA1 (0.42) | BRD4 | |
| SCHEMBL19663854 | 0.69 | — | — | |
| SCHEMBL23783391 | 0.67 | CECR2 (0.35) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17749858 | 0.64 | BRD9 (0.52) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17758546 | 0.60 | CA1 (0.42) | BRD4 | |
| SCHEMBL19658809 | 0.59 | BRD4 (0.38) | BRD4 | |
| SCHEMBL18499545 | 0.59 | ALDH1A1 (0.33) | BRD4 | |
| SCHEMBL24363723 | 0.58 | PDE4A (0.31) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL19278511 | 0.58 | RHEB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-10183009-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183009-B2 | Therapeutic compounds and uses thereof | BRD4, BRDT, BRPF3 | CECR2 246/4885BRD4 1/4885BRD9 12/4885 |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRPF3 | CECR2 246/4885BRD4 1/4885BRD9 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.