Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 15/20 | 0.73 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30117226 | 0.85 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL19643782 | 0.85 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL19644201 | 0.79 | CREBBP (0.76) | CREBBPBRD4PIK3CA | |
| SCHEMBL21023848 | 0.78 | CREBBP (0.69) | CREBBPPIK3CA | |
| SCHEMBL19644030 | 0.78 | CREBBP (0.63) | CREBBPBRD4PIK3CAPFKFB3 | |
| SCHEMBL22166179 | 0.74 | CREBBP (0.69) | CREBBPPIK3CA | |
| SCHEMBL19657623 | 0.72 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL24258486 | 0.72 | CREBBP (0.61) | CREBBPBRD4 | |
| SCHEMBL19657724 | 0.68 | CREBBP (0.50) | CREBBPBRD4 | |
| SCHEMBL19657733 | 0.68 | CREBBP (0.50) | CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |