Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 19/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657733 | 0.75 | CREBBP (0.50) | CREBBP | |
| SCHEMBL24258489 | 0.73 | CREBBP (0.56) | CREBBPBRD4EP300 | |
| SCHEMBL24258486 | 0.72 | CREBBP (0.61) | CREBBPBRD4 | |
| SCHEMBL21024011 | 0.71 | CREBBP (0.41) | CREBBPBRD4ALOX5APFEN1 | |
| SCHEMBL19657813 | 0.70 | CREBBP (0.44) | CREBBPBRD4ALOX5APFEN1 | |
| SCHEMBL19644030 | 0.70 | CREBBP (0.63) | CREBBPBRD4ALOX5APFEN1 | |
| SCHEMBL21024171 | 0.69 | CREBBP (0.62) | CREBBPBRD4EP300 | |
| SCHEMBL19644201 | 0.69 | CREBBP (0.76) | CREBBPBRD4 | |
| SCHEMBL19657625 | 0.68 | CREBBP (0.73) | CREBBPBRD4 | |
| SCHEMBL30117226 | 0.67 | CREBBP (1.00) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |