Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764844 | 0.93 | HTT (0.60) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL19652100 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL9144556 | 0.86 | HTT (0.51) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL19658635 | 0.85 | BCHE (0.49) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL19221832 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL5768608 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL20187093 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL3652558 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGRIN2BHTT | |
| SCHEMBL19063606 | 0.82 | KDM4E (0.53) | SMN1; SMN2NPC1RAB9AHTTTPSAB1 | |
| SCHEMBL30990345 | 0.82 | KDM4E (0.53) | SMN1; SMN2NPC1RAB9AHTTTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | SMN1; SMN2 1221/4885NPC1 1229/4885RAB9A 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.