Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.64 |
| ▸ | TUBB | P07437 | 2/20 | 0.64 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.64 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.64 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.64 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.64 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.64 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.64 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.64 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.64 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.64 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.64 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.64 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.64 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | TP53 | P04637 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 10/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880774 | 0.94 | BRAF (0.73) | BRAFTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1970288 | 0.90 | TUBB4A (0.68) | BRAFTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2977993 | 0.86 | MAPT (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1967979 | 0.86 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15152603 | 0.86 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2924324 | 0.84 | BRAF (0.91) | BRAFTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15152564 | 0.83 | MAPT (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2995123 | 0.83 | TUBB4A (0.93) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1966524 | 0.83 | NTRK1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL26908134 | 0.83 | TOP2A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334675-A1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010032195-A1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2010-03-25 | — | — | WO | disclosed |