Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834469 | 0.87 | USP2 (0.63) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL13853782 | 0.85 | USP2 (0.71) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL19652153 | 0.85 | USP2 (0.61) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL19658662 | 0.83 | USP2 (0.59) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL6246964 | 0.82 | HCAR1 (0.59) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL15825127 | 0.82 | USP2 (0.47) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL3730443 | 0.81 | DRD2 (0.72) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL13155876 | 0.81 | USP2 (0.56) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL432010 | 0.80 | DRD2 (0.65) | USP2KMT2ADRD2SLC6A4ALDH1A1 | |
| SCHEMBL13801310 | 0.78 | DRD2 (0.60) | USP2KMT2ADRD2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10258603-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10258603-B2 | Therapeutic compounds and uses thereof | BRD4, BRDT, BRD3 | USP2 3360/4885KMT2A 165/4885DRD2 2016/4885 |
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | USP2 3360/4885KMT2A 165/4885DRD2 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.