Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.65 |
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.63 |
| ▸ | RELA | Q04206 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971692 | 0.83 | NPC1 (0.69) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL27640883 | 0.82 | SORT1 (0.62) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL1998921 | 0.81 | F10 (0.60) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL28339146 | 0.80 | KMT2A (0.56) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL4857006 | 0.80 | RAB9A (0.56) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL12501925 | 0.80 | RAB9A (0.72) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL16318472 | 0.80 | DEGS1 (0.56) | RAB9ANPC1KMT2AMEN1F10 | |
| SCHEMBL3165548 | 0.79 | RAB9A (0.77) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL3151641 | 0.79 | SORT1 (0.61) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL3157401 | 0.79 | KMT2A (0.57) | RAB9ANPC1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |