SCHEMBL19660503

SCHEMBL19660503

c1ccc(-c2cccc(Nc3ccc4c5ccccc5c5ccccc5c4c3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.51
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
AR P10275 1/20 0.50
MGLL Q99685 1/20 0.47
MAPK10 P53779 1/20 0.46
MAPK14 Q16539 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
MAPK1 P28482 1/20 0.44
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24279339 0.89 MEN1 (0.56) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL31591202 0.89 MEN1 (0.56) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL30539515 0.88 MAPK10 (0.49) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL17742373 0.88 MAPK10 (0.49) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL1551938 0.86 ALDH1A1 (0.62) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL3181560 0.85 ALDH1A1 (0.67) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL29501296 0.85 ALDH1A1 (0.67) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL23608919 0.84 ALDH1A1 (0.54) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL23384417 0.84 ALDH1A1 (0.43) EPHX2ALDH1A1MEN1MAPTKMT2A
SCHEMBL24057750 0.84 ALDH1A1 (0.48) EPHX2ALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
US-20230009845-A1 ORGANIC ELECTRIC ELEMENT COMPRISING A PLURALITY OF EMISSION-AUXILIARY LAYERS AND ELECTRONIC DEVICE COMPRISING IT DUK SAN NEOLUX CO., LTD. (KR) 2023-01-12 US disclosed
WO-2022250244-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-01 WO disclosed
US-11205755-B2 Compound for organic electronic element, organic electronic element using same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-12-21 US disclosed
US-20190296248-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2019-09-26 US disclosed
US-20190229271-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRONIC ELEMENT DUK SAN NEOLUX CO., LTD. (KR) 2019-07-25 US disclosed
US-20190189927-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2019-06-20 US disclosed
WO-2018021737-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2018-02-01 WO disclosed
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed
WO-2017204556-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2017-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11205755-B2 Compound for organic electronic element, organic electronic element using same, and electronic device thereof PIEZO1, OR51E2, ORAI2 EPHX2 105/4885ALDH1A1 2676/4885MEN1 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.