SCHEMBL19660577

SCHEMBL19660577

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nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.35
AHCY P23526 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745985 0.73
SCHEMBL13412034 0.73
SCHEMBL880842 0.71 AHCY (0.36) AKR1B1AHCY
SCHEMBL20256972 0.71 AKR1B1 (0.35) AKR1B1AHCY
SCHEMBL17589372 0.71 AKR1B1 (0.35) AKR1B1AHCY
SCHEMBL14389187 0.70 AKR1B1 (0.39) AKR1B1AHCY
SCHEMBL17309109 0.70 AKR1B1 (0.33) AKR1B1AHCY
SCHEMBL18532037 0.68 AKR1B1 (0.37) AKR1B1AHCY
SCHEMBL3503633 0.67
SCHEMBL9070722 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017213854-A1 PHARMACEUTICAL COMPOSITION COMPRISING ETEPLIRSEN SAREPTA THERAPEUTICS, INC. (US) 2017-12-14 WO disclosed
WO-2017205879-A2 PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS SAREPTA THERAPEUTICS, INC. (US) 2017-11-30 WO disclosed
WO-2017205880-A1 PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS SAREPTA THERAPEUTICS, INC. (US) 2017-11-30 WO disclosed
WO-2017205513-A1 PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS SAREPTA THERAPEUTICS, INC. (US) 2017-11-30 WO disclosed
WO-2017205496-A1 PROCESSES FOR PREPARING OLIGOMERS SAREPTA THERAPEUTICS, INC. (US) 2017-11-30 WO disclosed