Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787244 | 0.94 | HDAC1 (0.47) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21787243 | 0.89 | MAPK1 (0.50) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21787242 | 0.81 | SMYD3 (0.49) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21786983 | 0.80 | HDAC6 (0.44) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19662620 | 0.79 | GRIN1 (0.47) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21787245 | 0.79 | HDAC1 (0.39) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11089138 | 0.79 | POLB (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL5924535 | 0.75 | POLB (0.52) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29833827 | 0.73 | POLB (0.74) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11089847 | 0.72 | CDK1 (0.56) | HDAC6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205336-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-30 | — | — | WO | disclosed |