Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271093 | 1.00 | SIRT3 (0.55) | SIRT3TDP1NPC1POLBRBP4 | |
| Methane SCHEMBL27522509 | 0.98 | SIRT3 (0.53) | SIRT3TDP1NPC1POLBRBP4 | |
| SCHEMBL9017980 | 0.87 | TDP1 (0.53) | SIRT3TDP1NPC1POLBRBP4 | |
| SCHEMBL9018018 | 0.86 | SIRT3 (0.51) | SIRT3TDP1NPC1POLBRBP4 | |
| SCHEMBL9017969 | 0.86 | SIRT3 (0.51) | SIRT3TDP1NPC1POLBRBP4 | |
| SCHEMBL4043333 | 0.85 | TDP1 (0.50) | SIRT3TDP1NPC1POLBMAPT | |
| SCHEMBL31144930 | 0.85 | TDP1 (0.50) | SIRT3TDP1NPC1POLBMAPT | |
| SCHEMBL27743576 | 0.85 | NPC1 (0.55) | SIRT3TDP1NPC1POLBRBP4 | |
| SCHEMBL15514535 | 0.83 | NPC1 (0.54) | SIRT3TDP1NPC1POLBRBP4 | |
| SCHEMBL379950 | 0.83 | POLB (0.54) | SIRT3TDP1NPC1POLBRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122004226-A | Detention spraying insecticidal composition and application thereof | 江苏优士化学有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-118206482-B | Synthesis method of 4-trifluoromethyl nicotinamide | 山东京博生物科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-116235858-B | Composition containing 4-trifluoromethyl nicotinamide and chemical pesticide and application thereof | 山东科大创业生物有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119278964-A | Composition containing 4-trifluoromethyl nicotinamide and botanical insecticide and application thereof | 山东科大创业生物有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119278965-A | Composition containing 4-trifluoromethyl nicotinamide and botanical insecticide and application thereof | 山东科大创业生物有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119176800-A | Pyridine thiophene acetamide compound and preparation method and application thereof | 盐城工学院 | 2024-12-24 | — | — | CN | claimed |
| CN-116172002-B | Composition containing 4-trifluoromethyl nicotinamide and microbial source pesticide and application thereof | 山东科大创业生物有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-116158445-B | Composition containing 4-trifluoromethyl nicotinamide and microbial pesticide and application thereof | 山东科大创业生物有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-116138274-B | Composition containing 4-trifluoromethyl nicotinamide and botanical insecticide and application thereof | 山东科大创业生物有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118206482-A | Synthesis method of 4-trifluoromethyl nicotinamide | 山东京博生物科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | SHERMOLOVICH YURIY GRIGORIEVIC (UA) | 2004-08-26 | — | — | US | claimed |
| CN-1419542-A | Heterocyclic acylsulfimide compounds, process for their preparation, compositions containing them and their use as pesticides | BAYER CROSCIENCE GMBH (DE) | 2003-05-21 | — | — | CN | claimed |
| EP-1274683-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2003-01-15 | — | — | EP | claimed |
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | AVENTIS CROPSCIENCE GMBH (DE) | 2002-03-14 | — | — | US | claimed |
| WO-2001070692-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2001-09-27 | — | — | WO | claimed |
| CN-1044233-C | Amide compounds and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1999-07-21 | — | — | CN | claimed |
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | claimed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | claimed |
| CN-1081670-A | Amide compound and salt thereof, their manufacturing process and pesticide composition thereof | ISHIHARA SANGYO KAISHA (JP) | 1994-02-09 | — | — | CN | claimed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | DDT, PTMS, TMT1A | SIRT3 247/4885TDP1 2703/4885NPC1 4510/4885 |
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | DDT, PTMS, TMT1A | SIRT3 247/4885TDP1 2703/4885NPC1 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.