Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018018 | 0.90 | SIRT3 (0.51) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL30271093 | 0.86 | SIRT3 (0.55) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL9017991 | 0.86 | SIRT3 (0.55) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL1966341 | 0.86 | SIRT3 (0.55) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL9017980 | 0.84 | TDP1 (0.53) | SIRT3TDP1NPC1POLBALDH1A1 | |
| Methane SCHEMBL27522509 | 0.84 | SIRT3 (0.53) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL8852563 | 0.76 | NPC1 (0.58) | NPC1POLBALDH1A1KDM4EHTT | |
| SCHEMBL31144930 | 0.75 | TDP1 (0.50) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL4043333 | 0.75 | TDP1 (0.50) | SIRT3TDP1NPC1POLBALDH1A1 | |
| SCHEMBL1330970 | 0.73 | TDP1 (0.67) | SIRT3TDP1ALDH1A1KDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1044233-C | Amide compounds and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| CN-1081670-A | Amide compound and salt thereof, their manufacturing process and pesticide composition thereof | ISHIHARA SANGYO KAISHA (JP) | 1994-02-09 | — | — | CN | disclosed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | disclosed |