Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271093 | 0.87 | SIRT3 (0.55) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL1966341 | 0.87 | SIRT3 (0.55) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| Methane SCHEMBL27522509 | 0.86 | SIRT3 (0.53) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL3934372 | 0.85 | KDM4C (0.48) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL9018018 | 0.84 | SIRT3 (0.51) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL9017969 | 0.84 | SIRT3 (0.51) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL9017991 | 0.80 | SIRT3 (0.55) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL4043333 | 0.76 | TDP1 (0.50) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL31144930 | 0.76 | TDP1 (0.50) | TDP1SIRT3KDM4EMAPTALDH1A1 | |
| SCHEMBL1330970 | 0.74 | TDP1 (0.67) | TDP1SIRT3KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | disclosed |