Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 10/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15693312 | 0.84 | ALDH1A1 (0.42) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL7909260 | 0.83 | CSNK2A1 (0.47) | CSNK2A1 | |
| SCHEMBL16957987 | 0.82 | ALDH1A1 (0.44) | MEN1ALDH1A1LMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL2282287 | 0.81 | CSNK2A1 (0.49) | CSNK2A1 | |
| SCHEMBL2440368 | 0.80 | CSNK2A1 (0.45) | CSNK2A1 | |
| SCHEMBL4550407 | 0.79 | CSNK2A1 (0.41) | CSNK2A1BACE1CTSDBACE2 | |
| SCHEMBL3397681 | 0.79 | ALDH1A1 (0.42) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL15711376 | 0.79 | CSNK2A1 (0.61) | CSNK2A1MEN1LMNAKMT2A | |
| SCHEMBL17159711 | 0.79 | MEN1 (0.40) | MEN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL13343804 | 0.79 | CYP1A2 (0.45) | CSNK2A1MEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914597-B1 | PYRAZOLOPYRIDINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2017-12-06 | — | — | EP | disclosed |