Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 11/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423595 | 0.85 | FFAR4 (0.43) | ALDH1A1MAPTPPARGPPARDPPARA | |
| SCHEMBL5184347 | 0.84 | PDE4A (0.43) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL3399129 | 0.81 | PPARG (0.38) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL15693312 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL5184176 | 0.80 | ALOX15 (0.39) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL16957987 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL19664448 | 0.79 | CSNK2A1 (0.47) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL195794 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL30536212 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL17159711 | 0.77 | MEN1 (0.40) | ALDH1A1MEN1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009103626-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |