Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.66 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966444 | 1.00 | MTNR1A (0.66) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1966085 | 0.91 | MTNR1A (0.69) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1969779 | 0.91 | MTNR1A (0.69) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1965540 | 0.84 | MTNR1A (0.73) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1965545 | 0.84 | MTNR1A (0.73) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1966352 | 0.83 | MTNR1B (0.74) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1966354 | 0.83 | MTNR1B (0.74) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1969011 | 0.83 | MTNR1A (0.67) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1969010 | 0.83 | MTNR1A (0.67) | MTNR1AMTNR1BNPY5RMEN1KMT2A | |
| SCHEMBL1965037 | 0.82 | MTNR1A (0.70) | MTNR1AMTNR1BNPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184594-A1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2012-07-19 | — | — | US | claimed |
| EP-2203422-B1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INT (ES) | 2011-06-22 | — | — | EP | claimed |
| EP-2203422-A1 | PHENYLPYRROLIDINE COMPOUNDS | Ferrer Internacional, S.A. (ES) | 2010-07-07 | — | — | EP | claimed |
| WO-2009053441-A1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2009-04-30 | — | — | WO | claimed |
| US-20120184594-A1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2012-07-19 | — | — | US | disclosed |
| EP-2203422-B1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INT (ES) | 2011-06-22 | — | — | EP | disclosed |
| EP-2203422-A1 | PHENYLPYRROLIDINE COMPOUNDS | Ferrer Internacional, S.A. (ES) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009053441-A1 | PHENYLPYRROLIDINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184594-A1 | PHENYLPYRROLIDINE COMPOUNDS | MTNR1A, MTNR1B, MC4R | MTNR1A 1/4885MTNR1B 2/4885NPY5R 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.