SCHEMBL19664772

SCHEMBL19664772

CC(C)=CCC/C(C)=C/Cc1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.58
PPARA Q07869 2/20 0.58
CTSL P07711 1/20 0.54
PTPN1 P18031 1/20 0.51
BACE1 P56817 1/20 0.51
MAOB P27338 5/20 0.51
APP P05067 2/20 0.51
KMT2A Q03164 3/20 0.50
GGPS1 O95749 1/20 0.50
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
CNR1 P21554 2/20 0.48
CNR2 P34972 2/20 0.48
TRPV1 Q8NER1 2/20 0.48
TRPA1 O75762 1/20 0.48
INHA P05111 1/20 0.48
SLC6A2 P23975 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5823582 1.00 PPARG (0.58) PPARGPPARACTSLPTPN1BACE1
SCHEMBL28252862 0.98 PPARG (0.57) PPARGPPARACTSLPTPN1BACE1
SCHEMBL2072101 0.86 KMT2A (0.52) PPARGPPARAPTPN1BACE1MAOB
SCHEMBL2072104 0.86 KMT2A (0.52) PPARGPPARAPTPN1BACE1MAOB
SCHEMBL2070992 0.84 GGPS1 (0.49) PPARGPPARAPTPN1BACE1MAOB
SCHEMBL3103575 0.84 KMT2A (0.53) PPARGPPARACTSLPTPN1BACE1
SCHEMBL2070993 0.84 GGPS1 (0.49) PPARGPPARAPTPN1BACE1MAOB
SCHEMBL3103585 0.84 KMT2A (0.53) PPARGPPARACTSLPTPN1BACE1
SCHEMBL31670205 0.84 TRPV1 (0.56) PPARGPPARAPTPN1BACE1KMT2A
SCHEMBL793954 0.84 TRPV1 (0.56) PPARGPPARAPTPN1BACE1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180035669-A1 ACETATE DERIVED COMPOUNDS FROM GERANYLORCINOL. SYNTHESIS PROCESS FOR OBTAINING SAID COMPOUNDS AND USE OF SAID COMPOUNDS AS ANTIFUNGAL AGAINST BOTRYTIS CINEREA UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA (CL) 2018-02-08 US disclosed
EP-3251509-A1 METHOD FOR THE SYNTHESIS OF LINEAR GERANYLORCINOL DERIVATIVES FROM GERANIOL AND ORCINOL, COMPOUNDS DERIVED FROM LINEAR GERANYLORCINOLS, AND USE OF SAID COMPOUNDS AS ANTIFUNGALS AGAINST BOTRYTIS CINEREA Universidad Tecnica Federico Santa Maria (USM) (CL) 2017-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180035669-A1 ACETATE DERIVED COMPOUNDS FROM GERANYLORCINOL. SYNTHESIS PROCESS FOR OBTAINING SAID COMPOUNDS AND USE OF SAID COMPOUNDS AS ANTIFUNGAL AGAINST BOTRYTIS CINEREA GGPS1, FNTA, FDPS PPARG 1217/4885PPARA 1033/4885CTSL 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.