Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27869222 | 0.89 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6361482 | 0.89 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| Acetone SCHEMBL14764809 | 0.89 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| Acetic Acid SCHEMBL4624184 | 0.88 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6897307 | 0.87 | CYP1A2 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL486901 | 0.87 | CYP1A2 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29114737 | 0.87 | CYP1A2 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8024040 | 0.87 | CYP1A2 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL715196 | 0.87 | CYP1A2 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27960807 | 0.87 | CYP1A2 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | HENKEL AG & CO. KGAA (DE) | 2019-09-12 | — | — | US | claimed |
| EP-3523414-A1 | CYCLIC KETALS AS FRAGRANCE PRECURSOR COMPOUNDS | Henkel AG & Co. KGaA (DE) | 2019-08-14 | — | — | EP | claimed |
| WO-2018095814-A1 | CYCLIC KETALS AS FRAGRANCE PRECURSOR COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2018-05-31 | — | — | WO | claimed |
| US-10941156-B2 | Cyclic ketals as fragrance precursor compounds | HENKEL AG & CO. KGAA (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | HENKEL AG & CO. KGAA (DE) | 2019-09-12 | — | — | US | disclosed |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941156-B2 | Cyclic ketals as fragrance precursor compounds | KCNK5, KLK5, KCNA1 | NPC1 2638/4885RAB9A 4153/4885SMN1; SMN2 3898/4885 |
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | KCNK5, KLK5, KCNA1 | NPC1 2638/4885RAB9A 4153/4885SMN1; SMN2 3898/4885 |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | TRPA1, CYP1A1, TRPV1 | NPC1 3689/4885RAB9A 3654/4885SMN1; SMN2 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.