SCHEMBL19665299

SCHEMBL19665299

O=c1oc2ccc(F)c(F)c2cc1CO[C@@H]1[C@@H](O)[C@@H](Sc2ccc(Cl)c(Cl)c2)O[C@H](CO)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 20/20 1.00
LGALS1 P09382 8/20 0.75
LGALS8 O00214 6/20 0.59
LGALS9 O00182 5/20 0.53
LGALS2 P05162 2/20 0.53
LGALS4 P56470 2/20 0.53
LGALS7; LGALS7B P47929 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23435225 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL17993073 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL19681090 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL23435260 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL19681042 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL16231593 0.87 LGALS3 (0.91) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL16226874 0.87 LGALS3 (0.91) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL16234116 0.87 LGALS3 (0.91) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL23435226 0.83 LGALS3 (0.72) LGALS3LGALS1LGALS8LGALS9LGALS2
SCHEMBL16234130 0.79 LGALS3 (0.73) LGALS3LGALS1LGALS8LGALS9LGALS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11377464-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2022-07-05 US claimed
EP-3828191-A2 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2021-06-02 EP claimed
US-20200407391-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2020-12-31 US claimed
US-10774102-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2020-09-15 US claimed
US-20170349619-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2017-12-07 US claimed
US-11919921-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2024-03-05 US disclosed
US-11377464-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2022-07-05 US disclosed
CN-113621005-A alpha-D-galactoside inhibitors of galectins 格莱克特生物技术公司 2021-11-09 CN disclosed
CN-107406478-B alpha-D-galactoside inhibitors of galectins 格莱克特生物技术公司 2021-07-27 CN disclosed
EP-3828191-A2 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2021-06-02 EP disclosed
EP-3250581-B1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2021-01-20 EP disclosed
US-20200407391-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2020-12-31 US disclosed
US-10774102-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2020-09-15 US disclosed
US-20170349619-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407391-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS LGALS1, LGALS3, LGALS2 LGALS3 2/4885LGALS1 1/4885LGALS8 6/4885
US-11377464-B2 Galactoside inhibitor of galectins LGALS3, LGALS1, LGALS2 LGALS3 1/4885LGALS1 2/4885LGALS8 6/4885
US-11919921-B2 Galactoside inhibitor of galectins LGALS3, LGALS1, LGALS2 LGALS3 1/4885LGALS1 2/4885LGALS8 6/4885
US-20170349619-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS LGALS3, LGALS1, LGALS2 LGALS3 1/4885LGALS1 2/4885LGALS8 6/4885
US-10774102-B2 Galactoside inhibitor of galectins LGALS3, LGALS1, LGALS2 LGALS3 1/4885LGALS1 2/4885LGALS8 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.