Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142398 | 0.87 | L3MBTL1 (0.47) | ALDH1A1MAPK1TSHRDDB1CRBN | |
| SCHEMBL12694398 | 0.75 | CRBN (0.57) | ALDH1A1MAPK1TSHRDDB1CRBN | |
| SCHEMBL2191627 | 0.74 | DDB1 (0.43) | ALDH1A1MAPK1TSHRDDB1CRBN | |
| SCHEMBL10622409 | 0.73 | PTAFR (0.32) | HPGD | |
| SCHEMBL20337367 | 0.72 | L3MBTL1 (0.53) | ALDH1A1MAPK1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL29191821 | 0.71 | EPHX2 (0.30) | — | |
| SCHEMBL600925 | 0.69 | L3MBTL1 (0.56) | ALDH1A1MAPK1TSHRDDB1CRBN | |
| SCHEMBL600924 | 0.69 | L3MBTL1 (0.56) | ALDH1A1MAPK1TSHRDDB1CRBN | |
| SCHEMBL12512638 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPK1TSHRL3MBTL1KDM4E | |
| SCHEMBL601653 | 0.67 | L3MBTL1 (0.59) | ALDH1A1MAPK1TSHRDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9109119-B2 | Chromophores, method for the preparation thereof, and use of same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2015-08-18 | — | — | US | disclosed |
| EP-2334739-B1 | NOVEL CHROMOPHORES, METHOD FOR THE PREPARATION THEREOF, AND USE OF SAME | CENTRE NAT RECH SCIENT (FR) | 2013-11-06 | — | — | EP | disclosed |
| US-20110172439-A1 | Novel Chromophores, Method for the Preparation Thereof, and Use of Same | Centre National Se La Recherche Scientifique-CNRS (FR) | 2011-07-14 | — | — | US | disclosed |
| EP-2334739-A2 | NOVEL CHROMOPHORES, METHOD FOR THE PREPARATION THEREOF, AND USE OF SAME | Centre National de la Recherche Scientifique - CNRS (FR) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010029274-A2 | NOVEL CHROMOPHORES, METHOD FOR THE PREPARATION THEREOF, AND USE OF SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172439-A1 | Novel Chromophores, Method for the Preparation Thereof, and Use of Same | C9, C5, C1S | ALDH1A1 2826/4885MAPK1 4098/4885TSHR 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.