Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347148 | 0.76 | CPN1 (0.38) | ALOX5CPN1CPB2OPRD1EPHX1 | |
| SCHEMBL3941287 | 0.75 | CPN1 (0.37) | ALOX5CPN1CPB2OPRD1EPHX1 | |
| SCHEMBL6230141 | 0.69 | CPN1 (0.42) | ALOX5CPN1CPB2OPRD1EPHX1 | |
| SCHEMBL29097223 | 0.69 | ALOX5 (0.44) | ALOX5 | |
| Hydrochloric Acid SCHEMBL6229690 | 0.68 | CPN1 (0.41) | ALOX5CPN1CPB2OPRD1KMT2A | |
| SCHEMBL18081016 | 0.67 | SLC6A2 (0.35) | ALOX5CPN1CPB2OPRD1SLC6A2 | |
| SCHEMBL528681 | 0.67 | SLC6A2 (0.35) | ALOX5CPN1CPB2OPRD1SLC6A2 | |
| SCHEMBL9732545 | 0.67 | CPN1 (0.40) | CPN1CPB2OPRD1EPHX1SMYD3 | |
| SCHEMBL27261240 | 0.67 | OPRD1 (0.54) | OPRD1SMYD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1938053 | 0.66 | CPN1 (0.41) | ALOX5CPN1CPB2OPRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464268-A1 | NOVEL COMPOUNDS | Chiesi Farmaceutici S.p.A. (IT) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017207432-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |