Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196311 | 0.86 | MAPT (0.41) | MAPTRXFP1TP53SMN1; SMN2NPY5R | |
| SCHEMBL197114 | 0.82 | MAPT (0.49) | IGF1RMAPTTP53SMN1; SMN2ACP1 | |
| SCHEMBL196681 | 0.82 | RXFP1 (0.53) | IGF1RMAPTRXFP1 | |
| SCHEMBL959150 | 0.81 | MEN1 (0.48) | MAPTRXFP1TP53SMN1; SMN2 | |
| SCHEMBL934924 | 0.80 | IGF1R (0.52) | IGF1RMAPTRXFP1TP53 | |
| SCHEMBL196063 | 0.74 | RXFP1 (0.60) | MAPTRXFP1 | |
| SCHEMBL196744 | 0.73 | MAPT (0.58) | MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL196512 | 0.73 | MAPT (0.55) | MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL17713545 | 0.73 | NPY5R (0.54) | IGF1RMAPTTP53SMN1; SMN2NPY5R | |
| SCHEMBL936997 | 0.72 | ADORA3 (0.52) | MAPTRXFP1TP53SMN1; SMN2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500255-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2323661-A1 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS | Universiteit Leiden (NL) | 2011-05-25 | — | — | EP | claimed |
| WO-2010020981-A1 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS | UNIVERSITEIT LEIDEN (NL) | 2010-02-25 | — | — | WO | claimed |