Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518653 | 0.84 | NLRP3 (0.57) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL5520049 | 0.83 | ALDH1A1 (0.58) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL12812272 | 0.82 | POLB (0.65) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL20194427 | 0.80 | NLRP3 (0.60) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL30013966 | 0.79 | ALDH1A1 (0.70) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL9177252 | 0.79 | ALDH1A1 (0.57) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL9801144 | 0.79 | NLRP3 (0.59) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL11414687 | 0.78 | POLB (0.61) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL11274661 | 0.78 | ALDH1A1 (0.50) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL25210146 | 0.77 | ALDH1A1 (0.68) | NLRP3ALDH1A1SMN1; SMN2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834547-B2 | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-12-05 | — | — | US | disclosed |