Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670158 | 0.91 | NOTUM (0.38) | MAT2ANOTUMMLLT1MAOAMAOB | |
| SCHEMBL19670512 | 0.87 | BTK (0.37) | WNT3ADYRK1A | |
| SCHEMBL19670571 | 0.86 | NOTUM (0.39) | MAT2ANOTUMMLLT1MAOAMAOB | |
| SCHEMBL16238356 | 0.83 | NOTUM (0.38) | MAT2ANOTUMMAOAMAOBF10 | |
| SCHEMBL19865050 | 0.82 | HTR2C (0.40) | WNT3A | |
| SCHEMBL16754329 | 0.81 | NOTUM (0.37) | MAT2ANOTUMMLLT1MAOAMAOB | |
| SCHEMBL19669970 | 0.79 | PIK3CA (0.36) | WNT3AHTT | |
| SCHEMBL19670405 | 0.79 | BRAF (0.40) | WNT3ADYRK1A | |
| SCHEMBL19670135 | 0.79 | MEN1 (0.41) | MAOAMAOBKDM4EHTT | |
| SCHEMBL16776212 | 0.74 | NOTUM (0.39) | MAT2ANOTUMMLLT1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |