Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 7/20 | 0.34 |
| ▸ | IDH2 | P48735 | 6/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670326 | 0.86 | SCN9A (0.35) | CNR2CNR1PIM1IDH2 | |
| SCHEMBL19670568 | 0.84 | IDH2 (0.38) | CNR2CNR1IDH2KDM4EHPGD | |
| SCHEMBL19670197 | 0.83 | CNR2 (0.35) | CNR2CNR1IDH2KDM1AKDM4E | |
| SCHEMBL19670566 | 0.82 | IDH2 (0.35) | CNR2CNR1IDH2KDM1APIM2 | |
| SCHEMBL19670330 | 0.82 | IDH2 (0.36) | CNR2CNR1IDH2KDM4EHPGD | |
| SCHEMBL19670570 | 0.81 | IDH2 (0.36) | CNR2CNR1IDH2PIM2KDM4E | |
| SCHEMBL17618370 | 0.80 | IDH2 (0.39) | IDH2KDM1AKDM4E | |
| SCHEMBL17618359 | 0.75 | KMT2A (0.39) | IDH2KDM1AKDM4E | |
| SCHEMBL20632424 | 0.73 | KDM1A (0.46) | CNR2CNR1IDH2KDM1AKDM4E | |
| SCHEMBL17618372 | 0.70 | IDH2 (0.40) | IDH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |