Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968408 | 0.80 | LCK (0.42) | LCKRORCSTING1PIK3CDPIK3CA | |
| SCHEMBL1966409 | 0.80 | LCK (0.42) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1964624 | 0.79 | LCK (0.45) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1967011 | 0.79 | LCK (0.45) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1965246 | 0.78 | LCK (0.39) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1965650 | 0.77 | LCK (0.43) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1964840 | 0.77 | LCK (0.47) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1967636 | 0.76 | LCK (0.46) | LCKRORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1967758 | 0.76 | LCK (0.45) | LCKRORCSTING1PIK3CDPIK3CA | |
| SCHEMBL1973510 | 0.75 | HSD17B10 (0.44) | LCKRORCPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | claimed |