Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 11/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967011 | 0.88 | LCK (0.45) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1965650 | 0.86 | LCK (0.43) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1967758 | 0.85 | LCK (0.45) | LCKRORCCYP2C9CSNK2A2CSNK2B | |
| SCHEMBL1967636 | 0.84 | LCK (0.46) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1966409 | 0.83 | LCK (0.42) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1973510 | 0.82 | HSD17B10 (0.44) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1964840 | 0.82 | LCK (0.47) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1964805 | 0.81 | KIF11 (0.41) | LCKRORCCYP2C9CSNK2A2CSNK2B | |
| SCHEMBL1967031 | 0.79 | LCK (0.42) | LCKRORCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1965823 | 0.79 | LCK (0.42) | LCKRORCCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | claimed |