Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.34 |
| ▸ | CDK8 | P49336 | 5/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670237 | 0.90 | PRKD1 (0.33) | — | |
| SCHEMBL19670690 | 0.87 | CYP2C19 (0.34) | CYP2C19PIK3CA | |
| SCHEMBL19706213 | 0.86 | PRKD1 (0.33) | — | |
| SCHEMBL17618655 | 0.84 | CCNC (0.39) | CCNCCDK8CYP2C19PIK3CANOTUM | |
| SCHEMBL19670488 | 0.80 | HPGD (0.33) | — | |
| SCHEMBL19670635 | 0.80 | PRKD1 (0.35) | — | |
| SCHEMBL19706309 | 0.80 | HRH3 (0.39) | — | |
| SCHEMBL19706211 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL19670673 | 0.79 | JAK3 (0.33) | CYP2C19PIK3CA | |
| SCHEMBL19670505 | 0.79 | PRKD1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |