Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 12/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19706309 | 0.92 | HRH3 (0.39) | PRKD1KITKARS1PRKD2 | |
| SCHEMBL19670635 | 0.85 | PRKD1 (0.35) | PRKD1KARS1PRKD2 | |
| SCHEMBL19706209 | 0.85 | SMPD3 (0.34) | PRKD1 | |
| SCHEMBL16754396 | 0.83 | PRKD1 (0.36) | PRKD1ACACBKARS1 | |
| SCHEMBL19706213 | 0.83 | PRKD1 (0.33) | PRKD1KARS1 | |
| SCHEMBL19670237 | 0.83 | PRKD1 (0.33) | PRKD1KARS1 | |
| SCHEMBL19706211 | 0.82 | SMN1; SMN2 (0.36) | PRKD1KARS1 | |
| SCHEMBL19706138 | 0.79 | WNT3A (0.33) | KIT | |
| SCHEMBL19670367 | 0.79 | CCNC (0.34) | — | |
| SCHEMBL19670673 | 0.78 | JAK3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |