Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 4/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19706213 | 0.90 | PRKD1 (0.33) | PRKD1PIM1KARS1HPGDHSD17B10 | |
| SCHEMBL19670367 | 0.90 | CCNC (0.34) | — | |
| SCHEMBL19670488 | 0.84 | HPGD (0.33) | HPGDHSD17B10DYRK1A | |
| SCHEMBL19670635 | 0.84 | PRKD1 (0.35) | PRKD1KARS1 | |
| SCHEMBL19706309 | 0.84 | HRH3 (0.39) | PRKD1KARS1 | |
| SCHEMBL19706211 | 0.83 | SMN1; SMN2 (0.36) | PRKD1PIM1KARS1 | |
| SCHEMBL19670673 | 0.83 | JAK3 (0.33) | — | |
| SCHEMBL17618678 | 0.83 | KMO (0.36) | PRKD1KMOKARS1RPS6KB1GSK3B | |
| SCHEMBL19670505 | 0.83 | PRKD1 (0.34) | PRKD1KARS1 | |
| SCHEMBL19706209 | 0.82 | SMPD3 (0.34) | PRKD1PIM1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |