Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754337 | 1.00 | ABL1 (0.35) | ABL1WNT3AMAPK1PRKD1PRKD2 | |
| SCHEMBL17618709 | 0.91 | ABL1 (0.37) | ABL1WNT3AMAPK1PRKD1JAK3 | |
| SCHEMBL16754575 | 0.89 | MAPK1 (0.35) | ABL1WNT3AMAPK1PRKD1JAK3 | |
| SCHEMBL16754333 | 0.89 | ABL1 (0.35) | ABL1WNT3AMAPK1PRKD1JAK3 | |
| SCHEMBL16754381 | 0.89 | GSK3B (0.34) | ABL1WNT3AMAPK1PRKD1PRKD2 | |
| SCHEMBL16238798 | 0.88 | WNT3A (0.40) | ABL1WNT3APRKD1PRKD2GRM5 | |
| SCHEMBL17778385 | 0.88 | WNT3A (0.40) | ABL1WNT3APRKD1PRKD2GRM5 | |
| SCHEMBL16754278 | 0.88 | WNT3A (0.40) | ABL1WNT3APRKD1PRKD2GRM5 | |
| SCHEMBL16754386 | 0.88 | WNT3A (0.36) | ABL1WNT3AMAPK1PRKD1JAK3 | |
| SCHEMBL17618707 | 0.88 | WNT3A (0.36) | ABL1WNT3AMAPK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |