Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 8/20 | 0.37 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238798 | 1.00 | WNT3A (0.40) | WNT3AGRM5PRKD1KARS1ABL1 | |
| SCHEMBL16754278 | 1.00 | WNT3A (0.40) | WNT3AGRM5PRKD1KARS1ABL1 | |
| SCHEMBL16754411 | 0.95 | GRM5 (0.42) | WNT3AGRM5PRKD1KARS1ABL1 | |
| SCHEMBL16754503 | 0.93 | FAAH (0.36) | PRKD1KARS1 | |
| SCHEMBL16754300 | 0.92 | PRKD1 (0.39) | PRKD1KARS1PRKD2 | |
| SCHEMBL17618709 | 0.92 | ABL1 (0.37) | WNT3AGRM5PRKD1ABL1 | |
| SCHEMBL16776516 | 0.91 | KARS1 (0.37) | PRKD1KARS1PRKD2 | |
| SCHEMBL17618518 | 0.91 | PIK3CA (0.39) | — | |
| SCHEMBL16754442 | 0.90 | FAAH (0.34) | PRKD1KARS1 | |
| SCHEMBL16754666 | 0.90 | KARS1 (0.37) | PRKD1KARS1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016081692-A2 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2016-05-26 | — | — | WO | disclosed |