Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.64 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14208311 | 0.95 | VDR (0.58) | VDRCYP24A1 | |
| SCHEMBL13218281 | 0.86 | VDR (0.68) | VDRCYP24A1 | |
| SCHEMBL13201355 | 0.86 | VDR (0.68) | VDRCYP24A1 | |
| SCHEMBL19288333 | 0.86 | VDR (0.68) | VDRCYP24A1 | |
| SCHEMBL4166112 | 0.86 | VDR (0.63) | VDRCYP24A1 | |
| SCHEMBL3524967 | 0.85 | VDR (0.67) | VDR | |
| SCHEMBL3525289 | 0.85 | VDR (0.67) | VDR | |
| SCHEMBL4164083 | 0.85 | VDR (0.69) | VDR | |
| SCHEMBL9070738 | 0.85 | VDR (0.71) | VDRCYP24A1 | |
| SCHEMBL3520409 | 0.83 | VDR (0.64) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834512-B2 | (22E)-2-methylene-26,27-cyclo-22-dehydro-1α-hydroxy-19-norvitamin D3 derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |