SCHEMBL1967075

SCHEMBL1967075

CC1CC(=O)N(Cc2ccccc2[N+](=O)[O-])C(=O)C1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.60
GSK3B P49841 14/20 0.57
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28663777 0.83 GSK3B (0.53) ACHEGSK3BALDH1A1TSHRCA12
SCHEMBL1964083 0.81 ACHE (0.66) ACHEGSK3BALDH1A1MEN1POLB
SCHEMBL1966497 0.80 ACHE (0.50) ACHEGSK3BALDH1A1TSHRCA12
SCHEMBL1963337 0.79 ACHE (0.53) ACHEGSK3BALDH1A1CA12CA9
SCHEMBL1965862 0.77 ACHE (0.50) ACHEGSK3BCA12CA9MEN1
SCHEMBL7114927 0.75 ACHE (0.56) ACHEGSK3BALDH1A1TSHRCA12
SCHEMBL4919438 0.75 ACHE (0.51) ACHEGSK3BALDH1A1TSHRCA12
SCHEMBL515217 0.75 ACHE (0.51) ACHEGSK3BALDH1A1TSHRCA12
SCHEMBL4047966 0.74 TYR (0.67) ACHEGSK3BALDH1A1TSHRCA12
SCHEMBL12511057 0.72 ACHE (0.74) ACHEALDH1A1TSHRMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed