Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | GSK3B | P49841 | 6/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | PER2 | O15055 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582291 | 0.81 | ACHE (0.62) | ACHESIRT2SIRT1KMT2AMEN1 | |
| SCHEMBL1967075 | 0.81 | ACHE (0.60) | ACHEGSK3BKMT2AMEN1POLB | |
| SCHEMBL13950136 | 0.80 | ACHE (0.59) | ACHEGSK3BKMT2AMEN1ALDH1A1 | |
| SCHEMBL1964382 | 0.79 | PER2 (0.46) | ACHESIRT2SIRT1KMT2AMEN1 | |
| SCHEMBL515217 | 0.79 | ACHE (0.51) | ACHEGSK3BSIRT2SIRT1KMT2A | |
| SCHEMBL26102230 | 0.76 | TDP1 (0.48) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1963337 | 0.75 | ACHE (0.53) | ACHEGSK3BSIRT2SIRT1POLB | |
| SCHEMBL15014611 | 0.75 | ACHE (0.56) | ACHEKMT2APOLBALDH1A1PER2 | |
| SCHEMBL25740975 | 0.75 | ACHE (0.56) | ACHEKMT2APOLBALDH1A1PER2 | |
| SCHEMBL25740974 | 0.75 | ACHE (0.56) | ACHEKMT2APOLBALDH1A1PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102137841-B | Ortho-substituted haloalkylsulfonanilide derivative and herbicide | NISSAN CHEMICAL IND LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-102137841-A | Ortho-substituted haloalkylsulfonanilide derivative and herbicide | NISSAN CHEMICAL IND LTD | 2011-07-27 | — | — | CN | disclosed |
| EP-2336104-A1 | ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2011-06-22 | — | — | EP | disclosed |