Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208892 | 1.00 | P2RY10 (0.47) | P2RY10USP2HTTLPAR1LPAR3 | |
| SCHEMBL2217525 | 1.00 | P2RY10 (0.47) | P2RY10USP2HTTLPAR1LPAR3 | |
| SCHEMBL2217519 | 1.00 | P2RY10 (0.47) | P2RY10USP2HTTLPAR1LPAR3 | |
| SCHEMBL2231310 | 1.00 | P2RY10 (0.47) | P2RY10USP2HTTLPAR1LPAR3 | |
| SCHEMBL17445655 | 0.93 | CASR (0.43) | P2RY10USP2LPAR1LPAR3PLA2G2A | |
| SCHEMBL25243275 | 0.93 | USP2 (0.50) | USP2HTTLPAR5CTSKPLA2G2A | |
| SCHEMBL25289434 | 0.93 | USP2 (0.50) | USP2HTTLPAR5CTSKPLA2G2A | |
| SCHEMBL2220171 | 0.93 | USP2 (0.50) | USP2HTTLPAR5CTSKPLA2G2A | |
| SCHEMBL25289433 | 0.93 | USP2 (0.50) | USP2HTTLPAR5CTSKPLA2G2A | |
| SCHEMBL1965094 | 0.93 | USP2 (0.50) | USP2HTTLPAR5CTSKPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |