SCHEMBL2220171

SCHEMBL2220171

CCCCCCCCCCCCCCCCCCOCC(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
HTT P42858 1/20 0.49
LPAR5 Q9H1C0 1/20 0.47
SPHK1 Q9NYA1 1/20 0.42
PLA2G4B P0C869 2/20 0.42
PLA2G2A P14555 2/20 0.41
PLA2G10 O15496 1/20 0.41
PLA2G1B P04054 1/20 0.41
PLA2G5 P39877 1/20 0.41
PLA2G2C Q5R387 1/20 0.40
TK1 P04183 1/20 0.40
CTSK P43235 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KIF11 P52732 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13105319 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL1965094 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL5793544 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL2231718 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL25289434 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL25243275 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL10950109 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL25289433 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL2311830 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B
SCHEMBL2213869 1.00 USP2 (0.50) USP2HTTLPAR5SPHK1PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58164596-A None JP disclosed
US-12594292-B2 Antiviral prodrugs, intermediate-and long-acting formulations and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-07 US disclosed
US-20250177428-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-06-05 US disclosed
US-20250034182-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2025-01-30 US disclosed
US-20250011358-A1 ANTIVIRAL PRODRUGS, PHARMACEUTICAL FORMULATIONS, AND METHODS UNIV CALIFORNIA (US) 2025-01-09 US disclosed
US-12173029-B2 Antiviral prodrugs, pharmaceutical formulations, and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-24 US disclosed
EP-4469061-A2 ANTIVIRAL PRODRUGS, INTERMEDIATE- AND LONG-ACTING FORMULATIONS AND METHODS The Regents of the University of California (US) 2024-12-04 EP disclosed
US-12116380-B2 Phospholipid compounds and methods of making and using the same GILEAD SCIENCES, INC. (US) 2024-10-15 US disclosed
CN-118591377-A Antiviral prodrugs, intermediate and long acting formulations and methods 加利福尼亚大学董事会 2024-09-03 CN disclosed
WO-2024159117-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS, AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-02 WO disclosed
EP-0184905-A1 2-Acetoacetylglycerol derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-06-18 EP disclosed
US-4576933-A Method of use of 1-(alkyl for alkylcarbanoyl)-2-carbamoylglycerol derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-18 US disclosed
EP-0171968-A1 Use of a phospholipid derivative Takeda Chemical Industries, Ltd. (JP) 1986-02-19 EP disclosed
US-4562179-A ANTITUMOR AND ANTICARCINOGENIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-12-31 US disclosed
EP-0071892-B1 PHOSPHOLIPID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-10-23 EP disclosed
EP-0157609-A2 Lipid derivatives their production and use Takeda Chemical Industries, Ltd. (JP) 1985-10-09 EP disclosed
EP-0148777-A2 Phospholipids, their production and use Takeda Chemical Industries, Ltd. (JP) 1985-07-17 EP disclosed
EP-0094186-A1 Glycerol derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-11-16 EP disclosed
JP-S58164596-A PHOSPHOLIPID DERIVATIVE, ITS PREPARATION AND ANTITUMOR AGENT CONTAINING THE SAME FUJISAWA PHARMACEUT CO LTD 1983-09-29 JP disclosed
EP-0089635-A2 Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594292-B2 Antiviral prodrugs, intermediate-and long-acting formulations and methods ACE2, SARS1, FURIN USP2 1686/4885HTT 2014/4885LPAR5 783/4885
US-12116380-B2 Phospholipid compounds and methods of making and using the same PHOSPHO1, SGMS1, SGMS2 USP2 3835/4885HTT 3369/4885LPAR5 65/4885
US-12173029-B2 Antiviral prodrugs, pharmaceutical formulations, and methods MTAP, SARS1, RNGTT USP2 2515/4885HTT 1997/4885LPAR5 2020/4885
US-20250034182-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PHOSPHO1, SGMS1, SGMS2 USP2 3835/4885HTT 3369/4885LPAR5 65/4885
US-20250177428-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS SARS1, ACE2, FURIN USP2 1637/4885HTT 2016/4885LPAR5 509/4885
US-20250011358-A1 ANTIVIRAL PRODRUGS, PHARMACEUTICAL FORMULATIONS, AND METHODS MTAP, SARS1, RNGTT USP2 2515/4885HTT 1997/4885LPAR5 2020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.