SCHEMBL2217525

SCHEMBL2217525

CCCCCCCCC=CCCCCCCCCOCC(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 1/20 0.47
USP2 O75604 1/20 0.43
HTT P42858 1/20 0.43
LPAR1 Q92633 2/20 0.42
LPAR3 Q9UBY5 2/20 0.42
LPAR5 Q9H1C0 1/20 0.41
CTSK P43235 1/20 0.40
SOAT2 O75908 1/20 0.38
SOAT1 P35610 1/20 0.38
PLA2G2A P14555 2/20 0.38
PLA2G10 O15496 1/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G5 P39877 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25208892 1.00 P2RY10 (0.47) P2RY10USP2HTTLPAR1LPAR3
SCHEMBL2217519 1.00 P2RY10 (0.47) P2RY10USP2HTTLPAR1LPAR3
SCHEMBL2231310 1.00 P2RY10 (0.47) P2RY10USP2HTTLPAR1LPAR3
SCHEMBL1967093 1.00 P2RY10 (0.47) P2RY10USP2HTTLPAR1LPAR3
SCHEMBL17445655 0.93 CASR (0.43) P2RY10USP2LPAR1LPAR3PLA2G2A
SCHEMBL25243275 0.93 USP2 (0.50) USP2HTTLPAR5CTSKPLA2G2A
SCHEMBL25289434 0.93 USP2 (0.50) USP2HTTLPAR5CTSKPLA2G2A
SCHEMBL2220171 0.93 USP2 (0.50) USP2HTTLPAR5CTSKPLA2G2A
SCHEMBL25289433 0.93 USP2 (0.50) USP2HTTLPAR5CTSKPLA2G2A
SCHEMBL1965094 0.93 USP2 (0.50) USP2HTTLPAR5CTSKPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110177156-A1 Sterol-Modified Amphiphilic Lipids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177156-A1 Sterol-Modified Amphiphilic Lipids SREBF1, SREBF2, SGMS1 P2RY10 4781/4885USP2 2160/4885HTT 2662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.