Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP8B1 | Q9UNU6 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971614 | 0.98 | P2RY12 (0.72) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1966936 | 0.96 | P2RY12 (0.71) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1968995 | 0.95 | P2RY12 (0.69) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1966316 | 0.94 | P2RY12 (0.76) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1970154 | 0.92 | P2RY12 (0.74) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1965163 | 0.91 | P2RY12 (0.75) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1970514 | 0.91 | P2RY12 (0.78) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1970141 | 0.91 | P2RY12 (0.78) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1964954 | 0.91 | P2RY12 (0.74) | P2RY12MEN1KMT2AHDAC6CYP8B1 | |
| SCHEMBL1967422 | 0.91 | P2RY12 (0.79) | P2RY12MEN1KMT2AHDAC6CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166121-A1 | FUSED HETEROCYCLIC COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2011-07-07 | — | — | US | disclosed |
| US-20110166121-A1 | FUSED HETEROCYCLIC COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2011-07-07 | — | — | US | disclosed |
| US-20110166121-A1 | FUSED HETEROCYCLIC COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2011-07-07 | — | — | US | disclosed |
| EP-2334689-A2 | FUSED HETEROCYCLIC COMPOUND | LG Life Sciences Ltd. (KR) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010027236-A2 | FUSED HETEROCYCLIC COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010027236-A2 | FUSED HETEROCYCLIC COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166121-A1 | FUSED HETEROCYCLIC COMPOUND | F2, PF4, F11 | P2RY12 127/4885MEN1 849/4885KMT2A 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.