SCHEMBL196727

SCHEMBL196727

O=CNc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28069204 0.98 GAA (0.53)
Hydrochloric Acid SCHEMBL26619691 0.98 GAA (0.53)
SCHEMBL7648977 0.81 GAA (0.47)
SCHEMBL10861721 0.80 GAA (0.49)
SCHEMBL10861712 0.80 GAA (0.49)
SCHEMBL2654544 0.80 CNR1 (0.52)
SCHEMBL28112593 0.79 TP53 (0.46)
SCHEMBL15798505 0.78
SCHEMBL1466400 0.78
SCHEMBL21820031 0.77 NAMPT (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018021-B2 Thiophene derivatives for the treatment of disorders caused by IgE UCB Biopharma SRL (BE) 2024-06-25 US claimed
CN-115417869-B Synthesis method of 6-bromoimidazole [1.2A ] pyridine-3-formamide 安徽大学 2024-06-11 CN claimed
US-20240092773-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2024-03-21 US claimed
CN-117560934-A Perovskite battery based on NIC interface modification and preparation method thereof 河南大学 2024-02-13 CN claimed
US-20240018140-A1 MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-01-18 US claimed
CN-117026682-A Paper leather production process 浙江一树纸业集团有限公司 2023-11-10 CN claimed
CN-116115819-B Developable in-situ crosslinking embolic composition and method of use thereof 北京冠合医疗科技有限公司 2023-11-10 CN claimed
EP-4213843-A2 MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Merck Sharp & Dohme LLC (US) 2023-07-26 EP claimed
CN-113514575-B Method for identifying and detecting manganese-induced sugarcane secretion 广西大学 2023-06-09 CN claimed
CN-116143687-A Preparation method of (R) -3-aminopiperidine dihydrochloride 山东汇智药物研究有限公司 2023-05-23 CN claimed
EP-0763524-A1 Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use SANKYO COMPANY LIMITED (JP) 1997-03-19 EP claimed
EP-0677054-A1 NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS PFIZER INC. (US) 1995-10-18 EP claimed
EP-0297621-B1 Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA (IT) 1994-09-21 EP claimed
WO-1994015944-A1 NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS PFIZER LIMITED (GB) 1994-07-21 WO claimed
US-5025034-A Thromboxane inhibitors NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-06-18 US claimed
US-4988701-A Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1991-01-29 US claimed
US-4945106-A Prostaglandins NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-07-31 US claimed
EP-0297621-A2 Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-01-04 EP claimed
US-4709023-A Process for the preparation of 7-amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate, and its use for the synthesis of β-lactam antibiotics BAYER AKTIENGESELLSCHAFT (DE) 1987-11-24 US claimed
EP-0162396-A2 Process for the preparation of 7-amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate, and its use in the synthesis of beta-lactam antibiotics BAYER AG (DE) 1985-11-27 EP claimed