Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196727 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28069204 | 0.78 | GAA (0.53) | TP53RAB9ANPC1PKMKDM4E | |
| Hydrochloric Acid SCHEMBL26619691 | 0.78 | GAA (0.53) | TP53RAB9ANPC1PKMKDM4E | |
| SCHEMBL9255913 | 0.74 | CTSD (0.59) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4718965 | 0.74 | ALDH1A1 (0.57) | RAB9ANPC1PKMKDM4EALDH1A1 | |
| SCHEMBL243768 | 0.73 | ALDH1A1 (0.56) | TP53KDM4EALDH1A1LMNAGAA | |
| SCHEMBL5266703 | 0.72 | — | — | |
| SCHEMBL18021901 | 0.72 | — | — | |
| SCHEMBL9551726 | 0.72 | — | — | |
| SCHEMBL27949708 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108395889-A | Mercury ion fluorescence probe and its application of benzimidazole [1,2-a] and pyridine derivatives | 泰山医学院 | 2018-08-14 | — | — | CN | claimed |
| CN-112592339-B | 1,3, 4-oxadiazole-2 (3H) -thione-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2022-06-07 | — | — | CN | disclosed |
| CN-112358466-B | 1,2, 4-triazole-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-10-26 | — | — | CN | disclosed |
| CN-112592339-A | 1,3, 4-oxadiazole-2 (3H) -thione-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-04-02 | — | — | CN | disclosed |
| CN-112358466-A | 1,2, 4-triazole-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-02-12 | — | — | CN | disclosed |
| CN-106146487-B | Pyridylmethyl dithiocarbonic acid hetero-aromatic ring alkyl esters compound and its preparation method and application | 北京大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-108602813-A | Heteroaryl hydroxypyrimidinone as apj receptor agonist | 百时美施贵宝公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108395889-A | Mercury ion fluorescence probe and its application of benzimidazole [1,2-a] and pyridine derivatives | 泰山医学院 | 2018-08-14 | — | — | CN | disclosed |
| CN-107531692-A | Therapeutic compounds and application thereof | 基因泰克公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107400131-A | Eliquis derivative and its production and use | 沈阳药科大学 | 2017-11-28 | — | — | CN | disclosed |
| CN-104955824-B | It is used as the aminopyrimidine compounds of the inhibitor of the EGFR mutant containing T790M | 豪夫迈·罗氏有限公司 | 2017-09-22 | — | — | CN | disclosed |
| CN-106146487-A | Pyridylmethyl dithiocarbonic acid hetero-aromatic ring alkyl esters compound and its production and use | 北京大学 | 2016-11-23 | — | — | CN | disclosed |