Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formanilide SCHEMBL7025878 | 0.82 | ALDH1A1 (0.59) | GAALMNAALDH1A1MAPTNPC1 | |
| SCHEMBL196727 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28069204 | 0.79 | GAA (0.53) | GAALMNAALDH1A1TP53NPC1 | |
| Hydrochloric Acid SCHEMBL26619691 | 0.79 | GAA (0.53) | GAALMNAALDH1A1TP53NPC1 | |
| SCHEMBL7029152 | 0.70 | NPC1 (0.39) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10861712 | 0.65 | GAA (0.49) | GAALMNAALDH1A1MAPTTP53 | |
| SCHEMBL10861721 | 0.65 | GAA (0.49) | GAALMNAALDH1A1MAPTTP53 | |
| SCHEMBL3954733 | 0.65 | GAA (0.57) | GAALMNACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL2654544 | 0.65 | CNR1 (0.52) | CYP11B1CYP11B2ALDH1A1MEN1 | |
| SCHEMBL28112593 | 0.64 | TP53 (0.46) | GAALMNAALDH1A1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002041871-A2 | COMPOSITION COMPRISING AN IMEXON OR DERIVATIVES THEREOF AND LIPIDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-05-30 | — | — | WO | disclosed |