SCHEMBL196728

SCHEMBL196728

CC(C)(CC1CC2C=CC1C2)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.43
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 3/20 0.39
LMNA P02545 2/20 0.36
PKM P14618 3/20 0.36
TSHR P16473 1/20 0.35
MAPT P10636 2/20 0.34
MAPK1 P28482 1/20 0.34
EPHX2 P34913 2/20 0.34
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5833511 0.87 POLB (0.33) KDM4ETDP1POLB
SCHEMBL4271968 0.82 KDM4E (0.37) KDM4EALDH1A1TDP1LMNAPKM
SCHEMBL13346658 0.80 KDM4E (0.41) KDM4EALDH1A1TDP1LMNAPKM
SCHEMBL15803193 0.78 KDM4E (0.43) KDM4EALDH1A1TDP1LMNATSHR
SCHEMBL12357865 0.78 KDM4E (0.43) KDM4EALDH1A1TDP1LMNATSHR
SCHEMBL15466780 0.77 KDM4E (0.46) KDM4EALDH1A1TDP1LMNATSHR
SCHEMBL6550594 0.77 KDM4E (0.37) KDM4EALDH1A1TDP1LMNAPKM
SCHEMBL6548933 0.76 KDM4E (0.36) KDM4EALDH1A1TDP1PKMTSHR
SCHEMBL6549460 0.76 KDM4E (0.36) KDM4EALDH1A1TDP1PKMTSHR
SCHEMBL6550648 0.76 EPHX2 (0.38) KDM4EALDH1A1TDP1PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660561-B1 PHOTOSENSITIVE SILSESQUIOXANE RESIN DOW CORNING (US) 2014-02-12 EP claimed
US-8470944-B2 Polynorbornene pervaporation membrane films, preparation and use thereof PROMERUS, LLC (US) 2013-06-25 US claimed
US-20120283404-A1 Polynorbornene Pervaporation Membrane Films, Preparation and Use Thereof PROMERUS LLC (US) 2012-11-08 US claimed
US-7625687-B2 Silsesquioxane resin DOW CORNING CORPORATION (US) 2009-12-01 US claimed
US-20070281242-A1 Silsesquioxane Resin DOW SILICONES CORPORATION 2007-12-06 US claimed
EP-1660561-A2 PHOTOSENSITIVE SILSESQUIOXANE RESIN Dow Corning Corporation (US) 2006-05-31 EP claimed
WO-2005007747-A2 PHOTOSENSITIVE SILSESQUIOXANE RESIN DOW CORNING CORPORATION (US) 2005-01-27 WO claimed
US-8678203-B2 Polynorbornene pervaporation membrane films, preparation and use thereof PROMERUS, LLC (US) 2014-03-25 US disclosed
EP-1660561-B1 PHOTOSENSITIVE SILSESQUIOXANE RESIN DOW CORNING (US) 2014-02-12 EP disclosed
US-8609574-B2 In situ olefin polymerization catalyst system PROMERUS LLC (US) 2013-12-17 US disclosed
US-20130292872-A1 Polynorbornene Pervaporation Membrane Films, Preparation and Use Thereof PROMERUS, LLC 2013-11-07 US disclosed
US-8524439-B2 Silsesquioxane resin systems with base additives bearing electron-attracting functionalities DOW CORNING CORPORATION (US) 2013-09-03 US disclosed
US-8470944-B2 Polynorbornene pervaporation membrane films, preparation and use thereof PROMERUS, LLC (US) 2013-06-25 US disclosed
WO-2005007747-A2 PHOTOSENSITIVE SILSESQUIOXANE RESIN DOW CORNING CORPORATION (US) 2005-01-27 WO disclosed
EP-1167349-B1 Chemical amplifying type positive resist composition SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6818376-B2 OVERCOATING SEMICONDUCTOR SUBSTRATE WITH PHOTOSENSITIVE POLYMER; EXPOSURE TO RADIATION IN PRESENCE OF ACID GENERATOR HYNIX SEMICONDUCTOR INC. (KR) 2004-11-16 US disclosed
US-6548220-B2 Containing acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed
US-6403281-B1 ALKYLENE GLYCOL DI(METH)ACRYLATE OR ALKYLENE GLYCOL DI(2-NORBORNENE-5-CARBOXYLATE) CROSSLINKING MONOMERS; DURABILITY, CONTRAST, RESOLUTION, ADHESION; PHOTOLITHOGRAPHY; SEMICONDUCTORS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-06-11 US disclosed
US-20020015913-A1 Chemical amplifying type positive resist composition and sulfonium salt SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-07 US disclosed
EP-1167349-A1 Chemical amplifying type positive resist composition and sulfonium salt SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-02 EP disclosed