SCHEMBL4271968

SCHEMBL4271968

CC(C)(C)OC(=O)C(C)(C)CC1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.37
ALDH1A1 P00352 4/20 0.36
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 3/20 0.34
LMNA P02545 1/20 0.33
PKM P14618 3/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
EPHX2 P34913 2/20 0.32
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7146563 0.89 KDM4E (0.36) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL196728 0.82 KDM4E (0.43) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL4379431 0.79 KDM4E (0.38) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL3367438 0.77 KDM4E (0.33) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL3364020 0.77 KDM4E (0.33) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL19813191 0.77 KDM4E (0.36) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL32688567 0.76 MMP8 (0.41) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL19822715 0.76 EPHX1 (0.37) KDM4EALDH1A1TDP1LMNAEPHX2
SCHEMBL24355008 0.76 KDM4E (0.34) KDM4EALDH1A1POLBALOX15TDP1
SCHEMBL5417038 0.75 KDM4E (0.35) KDM4EALDH1A1POLBALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090292088-A1 PROCESS FOR PRODUCTION OF CYCLIC OLEFIN ADDITION POLYMER JSR CORPORATION (JP) 2009-11-26 US disclosed
EP-1961774-A1 PROCESS FOR PRODUCTION OF CYCLIC OLEFIN ADDITION POLYMER JSR Corporation (JP) 2008-08-27 EP disclosed