SCHEMBL6549460

SCHEMBL6549460

CC(CC1CC2C=CC1C2)(C(=O)O)C1CCC(O)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.36
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
TSHR P16473 1/20 0.32
PKM P14618 3/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP13 P45452 1/20 0.31
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548933 0.89 KDM4E (0.36) KDM4EALDH1A1TDP1TSHRPKM
SCHEMBL6550594 0.88 KDM4E (0.37) KDM4EALDH1A1TDP1TSHRPKM
SCHEMBL6551075 0.84 KDM4E (0.35) KDM4EALDH1A1TDP1TSHRPKM
SCHEMBL196728 0.76 KDM4E (0.43) KDM4EALDH1A1TDP1TSHRPKM
SCHEMBL13346658 0.71 KDM4E (0.41) KDM4EALDH1A1TDP1TSHRPKM
SCHEMBL15803193 0.69 KDM4E (0.43) KDM4EALDH1A1TDP1TSHR
SCHEMBL12357865 0.69 KDM4E (0.43) KDM4EALDH1A1TDP1TSHR
SCHEMBL17729244 0.69 SHBG (0.33) MMP2MMP3MMP13
SCHEMBL15466780 0.69 KDM4E (0.46) KDM4EALDH1A1TDP1TSHR
SCHEMBL5833511 0.68 POLB (0.33) KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167349-B1 Chemical amplifying type positive resist composition SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6548220-B2 Containing acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed