Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114421 | 1.00 | TSHR (1.00) | TSHRTRPA1LMNAMAPK1AOC3 | |
| SCHEMBL6061809 | 1.00 | TSHR (1.00) | TSHRTRPA1LMNAMAPK1AOC3 | |
| SCHEMBL1820543 | 1.00 | TSHR (1.00) | TSHRTRPA1LMNAMAPK1AOC3 | |
| Acetic Acid SCHEMBL7763816 | 0.89 | TSHR (0.79) | TSHRTRPA1LMNAMAPK1CACNA2D1 | |
| SCHEMBL6056000 | 0.89 | TSHR (0.79) | TSHRTRPA1LMNAALDH1A1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL16058242 | 0.87 | TSHR (0.76) | TSHRTRPA1LMNAMAPK1ALDH1A1 | |
| SCHEMBL8019014 | 0.86 | TSHR (0.75) | TSHRTRPA1ALDH1A1 | |
| Dimethylketone Cyanohydrin SCHEMBL6357582 | 0.85 | TSHR (0.73) | TSHRTRPA1LMNAMAPK1AOC3 | |
| Pentane SCHEMBL28983003 | 0.85 | TSHR (0.73) | TSHRTRPA1LMNAAOC3CACNA2D1 | |
| Mandelic Acid SCHEMBL5320867 | 0.85 | TSHR (0.73) | TSHRTRPA1LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2089 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109600-A1 | PROCESS FOR PREPARATION OF SULFONYL PYRAZOLONES | ADAMA AGAN LTD. (IL) | 2025-05-30 | — | — | WO | claimed |
| CN-119707746-A | Mandelonitrile alcohol ester compound and application thereof | 江苏扬农化工股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119632035-A | Tonsillitis and isothiocyanate compound insecticidal composition, preparation and application thereof | 西北农林科技大学 | 2025-03-18 | — | — | CN | claimed |
| US-20250084395-A1 | ENGINEERED NITRILASES FOR BIOCATALYSIS | KCAT ENZYMATIC PRIVATE LIMITED (IN) | 2025-03-13 | — | — | US | claimed |
| WO-2025053791-A1 | ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2025-03-13 | — | — | WO | claimed |
| CN-113866321-B | Detection method of body-building and digestion-promoting liquid | 云南省食品药品监督检验研究院 | 2024-11-22 | — | — | CN | claimed |
| CN-114410699-B | Method for producing R-mandelic acid by biocatalysis | 安徽泰格生物科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-113336636-B | Synthesis process of DL-mandelic acid with high yield | 湖州柏特生物科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-113265392-B | Cyano-group transfer catalyst and preparation method thereof | 山东华素制药有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115770531-A | Mandelic acid production system and technology thereof | 安徽中山化工有限公司 | 2023-03-10 | — | — | CN | claimed |
| EP-0132392-A2 | Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols | ICI AUSTRALIA LIMITED (AU) | 1985-01-30 | — | — | EP | claimed |
| US-4482760-A | HYDROGENATING A CYANOHYDRIN | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | claimed |
| EP-0025262-B1 | ALPHA-THIO-ALPHA-ARYL-SUBSTITUTED ALKANONITRILES, PROCESS FOR THEIR PREPARATION, PROCESS FOR PREPARING ALPHA-ARYL-SUBSTITUTED ALKANONITRILES AND THE CORRESPONDING CARBOXYLIC ACIDS THEREFROM AND PROCESS FOR PREPARING INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1983-10-05 | — | — | EP | claimed |
| US-4378319-A | Process for the manufacture of aromatic cyanides | A. H. MARKS & CO., LIMITED (GB) | 1983-03-29 | — | — | US | claimed |
| EP-0071568-A1 | Mandelic acid derivatives, process for their preparation and their microbicidal application | CIBA-GEIGY AG (CH) | 1983-02-09 | — | — | EP | claimed |
| US-4369322-A | WITH CYANOGEN CHLORIDE | DEGUSSA AG (DE) | 1983-01-18 | — | — | US | claimed |
| EP-0003242-B1 | PROCESS FOR THE PREPARATION OF ALPHA-CYANOBENZYL ESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-01-20 | — | — | EP | claimed |
| EP-0025262-A2 | Alpha-thio-alpha-aryl-substituted alkanonitriles, process for their preparation, process for preparing alpha-aryl-substituted alkanonitriles and the corresponding carboxylic acids therefrom and process for preparing intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-03-18 | — | — | EP | claimed |
| EP-0003242-A1 | Process for the preparation of alpha-cyanobenzyl esters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-08-08 | — | — | EP | claimed |
| US-4153626-A | Preparation of α-cyanobenzyl esters | SHELL OIL COMPANY (US) | 1979-05-08 | — | — | US | claimed |