Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114421 | 0.85 | TSHR (1.00) | TSHRTRPA1AOC3CACNA2D1CACNB2 | |
| SCHEMBL196731 | 0.85 | TSHR (1.00) | TSHRTRPA1AOC3CACNA2D1CACNB2 | |
| SCHEMBL6061809 | 0.85 | TSHR (1.00) | TSHRTRPA1AOC3CACNA2D1CACNB2 | |
| SCHEMBL1820543 | 0.85 | TSHR (1.00) | TSHRTRPA1AOC3CACNA2D1CACNB2 | |
| Acetic Acid SCHEMBL7763816 | 0.80 | TSHR (0.79) | TSHRTRPA1CACNA2D1CACNB2CACNA1C | |
| Pentane SCHEMBL28983003 | 0.77 | TSHR (0.73) | TSHRTRPA1AOC3CACNA2D1CACNB2 | |
| SCHEMBL6056000 | 0.76 | TSHR (0.79) | TSHRTRPA1LMNAALDH1A1 | |
| Benzoic Acid SCHEMBL16058242 | 0.74 | TSHR (0.76) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL28140301 | 0.74 | TSHR (0.68) | TSHRTRPA1AOC3CACNA2D1CACNB2 | |
| SCHEMBL8019014 | 0.74 | TSHR (0.75) | TSHRTRPA1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176116-A1 | Process for producing a-hydroxy acid ammonium salt | NIPPON SODA CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1466984-A1 | PROCESS FOR PRODUCING A-HYDROXY ACID AMMONIUM SALT | NIPPON SODA CO., LTD. (JP) | 2004-10-13 | — | — | EP | disclosed |