Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970517 | 0.81 | MEN1 (0.56) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL10363694 | 0.80 | MAPT (0.63) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL1970194 | 0.77 | MAPT (0.53) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL1965768 | 0.74 | MAPT (0.56) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL10355375 | 0.73 | MEN1 (0.64) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL5364455 | 0.72 | MAPT (0.77) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL11466661 | 0.72 | MAPT (0.61) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL9824981 | 0.72 | MAPT (1.00) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL3230944 | 0.72 | MEN1 (0.55) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL1967989 | 0.71 | MAPT (0.47) | MAPTCYP3A4KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172099-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| EP-2334649-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THEIR USE AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010031847-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THEIR USE AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172099-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | COX4I1, CYP2C19, CYP3A43 | MAPT 513/4885CYP3A4 4/4885KMT2A 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.