Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417105 | 0.84 | PTPN22 (0.58) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL29589326 | 0.78 | HSD17B10 (0.58) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL18600578 | 0.78 | HSD17B10 (0.58) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL380657 | 0.77 | CYP1A2 (0.65) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL10433287 | 0.77 | ALDH1A1 (0.53) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL17081238 | 0.77 | POLB (0.57) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL11076291 | 0.76 | HPRT1 (0.58) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL2467605 | 0.75 | CYP1A2 (0.62) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| Methane SCHEMBL8622876 | 0.75 | CYP1A2 (0.62) | PTPN22CYP1A2POLBHSD17B10USP2 | |
| SCHEMBL10433286 | 0.73 | PTPN22 (0.46) | PTPN22CYP1A2POLBHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114102-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |