Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417105 | 0.84 | PTPN22 (0.58) | POLBPTPN22HSD17B10CYP1A2USP2 | |
| SCHEMBL10433287 | 0.77 | ALDH1A1 (0.53) | POLBPTPN22HSD17B10CYP1A2USP2 | |
| SCHEMBL19673698 | 0.77 | PTPN22 (0.50) | POLBPTPN22HSD17B10CYP1A2USP2 | |
| SCHEMBL11076291 | 0.76 | HPRT1 (0.58) | POLBPTPN22HSD17B10CYP1A2USP2 | |
| SCHEMBL16781267 | 0.76 | HPRT1 (0.58) | POLBHSD17B10CYP1A2USP2CYP2C9 | |
| SCHEMBL28412121 | 0.75 | HPGD (0.39) | POLBPTPN22HSD17B10CYP1A2MEN1 | |
| SCHEMBL17063693 | 0.75 | HPGD (0.39) | POLBPTPN22HSD17B10CYP1A2MEN1 | |
| SCHEMBL29589326 | 0.74 | HSD17B10 (0.58) | POLBPTPN22HSD17B10CYP1A2USP2 | |
| SCHEMBL18600578 | 0.74 | HSD17B10 (0.58) | POLBPTPN22HSD17B10CYP1A2USP2 | |
| 1-Naphthol SCHEMBL6471543 | 0.74 | CYP1A2 (0.68) | POLBPTPN22HSD17B10CYP1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200303649-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| US-20200303649-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| US-10727413-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2020-07-28 | — | — | US | disclosed |
| US-10727413-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2020-07-28 | — | — | US | disclosed |
| CN-110698351-A | Material for electronic devices | 默克专利有限公司 | 2020-01-17 | — | — | CN | disclosed |
| EP-3114102-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |
| EP-3114102-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| CN-106132910-A | Material for electronic devices | 默克专利有限公司 | 2016-11-16 | — | — | CN | disclosed |
| WO-2015131976-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10727413-B2 | Materials for electronic devices | EED, OCIAD2, JUND | POLB 1588/4885PTPN22 4449/4885HSD17B10 1273/4885 |
| US-20200303649-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, OCIAD2, JUND | POLB 1588/4885PTPN22 4449/4885HSD17B10 1273/4885 |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, OCIAD2, JUND | POLB 1588/4885PTPN22 4449/4885HSD17B10 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.